Covance

  • Metabolism Internship

    Job Location(s) US-WI-Madison
    Job Number
    2018-25032
    Job Category
    Scientific Entry Level
    Position Type
    Intern
  • Job Overview

    Exciting Opportunity to be part of the Covance 2019 Global Internship Program! We offer our interns real work assignments that compliment an education in STEM+ Healthcare disciplines, are challenging and recognized to the organization as valuable. Our interns have the opportunity to showcase their work, allowing them to demonstrate their achievements to Covance senior management, their supervisor and mentors. Each intern class participates in a group philanthropic project allowing them to see firsthand how Covance is dedicated to its community. In addition, Covance encourages professional development and career exploration through program workshops, each designed to help students prepare for a thriving career in our industry.

     


    H2B Sponsorship not eligible for this position

     

     

    The Department of Metabolism is currently soliciting CVs for a summer intern employment opportunity. The intern may conduct one or more (time permitting) of the following studies to support metabolite identification (Met ID) efforts: 1) Establish collision cross section (CCS) of metabolites, as determined by ion mobility (IM), as a reliable measurement to characterize and differentiate multiple sites of glucuronidation and sulfation. 2) Establish rapid Met ID of PK samples as a service line extension and compare metabolites to those generated from in-vitro incubations. 3) Establish CCS of metabolites, as determined by IM, as a reliable measurement to characterize soft nucleophiles via glutathione (GSH) and related thiol trapping incubations. These studies will be designed to investigate and develop new technologies to continue to provide service offerings at the forefront of science. Model systems, data and metrics generated should assist in Covance business decisions regarding the cost and capability to offer these services to clients.

    Education/Qualifications

    Prerequisite: The applicant should be in a graduate or undergraduate program focused on biology, chemistry, or related field with at least 1 semester of organic chemistry and 1 semester of analytical chemistry and/or instrumental analysis.

    Experience

    Intern will learn and be able to demonstrate the following deliverables, as applicable:
    • Ability to perform in-vitro incubations, possibly using automated systems (robotics)
    • Knowledge of LCMS operation and sample analysis
    • Knowledge of calculations involved in creating working solutions: cell culture medium, test article preparations, incubation solution, mobile phase preparation etc.
    • Data analysis and reporting; ability to interpret data and to make data-based decisions

    The intern will have the opportunity to present his/her work to Covance senior management, supervisor and mentor.

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